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Pere Santamaria Selected Research

Glucose-6-Phosphatase (Glucose 6 Phosphatase)

11/2013DEC-205-mediated antigen targeting to steady-state dendritic cells induces deletion of diabetogenic CD8⁺ T cells independently of PD-1 and PD-L1.
9/2012Autoantigen recognition is required for recruitment of IGRP(206-214)-autoreactive CD8+ T cells but is dispensable for tolerance.
1/2010Idd9.1 locus controls the suppressive activity of FoxP3+CD4+CD25+ regulatory T-cells.
8/2009Spontaneous autoimmunity sufficiently potent to induce diabetes mellitus is insufficient to protect against insulinoma.
7/2006Modeling competition among autoreactive CD8+ T cells in autoimmune diabetes: implications for antigen-specific therapy.
6/2005Prevention of diabetes by manipulation of anti-IGRP autoimmunity: high efficiency of a low-affinity peptide.

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Pere Santamaria Research Topics

Disease

38Type 1 Diabetes Mellitus (Autoimmune Diabetes)
11/2021 - 02/2002
29Autoimmune Diseases (Autoimmune Disease)
01/2022 - 01/2003
10Inflammation (Inflammations)
01/2021 - 02/2003
5Neoplasms (Cancer)
01/2020 - 08/2009
3COVID-19
01/2021 - 01/2021
3Infections
01/2019 - 05/2010
3Disease Progression
06/2008 - 07/2006
2Common Cold
01/2021 - 01/2021
2Autoimmune Hepatitis
11/2020 - 01/2019
2Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental)
11/2020 - 01/2020
2Contact Dermatitis (Eczema, Contact)
06/2008 - 05/2004
1Reinfection
01/2021
1Muscle Cramp (Cramp)
01/2021
1Biliary Liver Cirrhosis (Primary Biliary Cirrhosis)
01/2019
1Sclerosing Cholangitis
01/2019
1Inflammatory Bowel Diseases (Inflammatory Bowel Disease)
10/2017
1Colitis
10/2017
1Rheumatoid Arthritis
10/2013
1Multiple Sclerosis
10/2013
1Genetic Predisposition to Disease (Genetic Predisposition)
10/2013
1Disease Resistance
02/2013
1Insulinoma
08/2009
1Insulin Resistance
12/2006
1Crohn Disease (Crohn's Disease)
06/2006
1Arthritis (Polyarthritis)
06/2006
1Diabetes Mellitus
06/2006
1Starvation
06/2006
1Myotonic Dystrophy (Dystrophia Myotonica)
12/2004
1Prediabetic State (Prediabetes)
02/2003
1Endotoxemia
07/2002

Drug/Important Bio-Agent (IBA)

23AntigensIBA
01/2022 - 02/2002
15Insulin (Novolin)FDA Link
11/2021 - 01/2003
15Peptides (Polypeptides)IBA
10/2021 - 01/2003
10Proteins (Proteins, Gene)FDA Link
01/2021 - 06/2005
8CytokinesIBA
01/2021 - 01/2003
7AutoantigensIBA
01/2021 - 08/2009
6EpitopesIBA
11/2020 - 06/2005
6Glucose-6-Phosphatase (Glucose 6 Phosphatase)IBA
11/2013 - 06/2005
5T-Cell Antigen Receptors (T-Cell Receptor)IBA
01/2010 - 02/2003
3Interleukin-2 (IL2)IBA
10/2016 - 03/2007
3Histocompatibility Antigens Class IIIBA
07/2013 - 02/2002
2Antigen-Antibody Complex (Immune Complex)IBA
01/2021 - 01/2018
2AntibodiesIBA
01/2021 - 01/2021
2Neoplasm Antigens (Tumor Antigens)IBA
01/2015 - 02/2012
2AutoantibodiesIBA
12/2013 - 02/2003
2InterleukinsIBA
01/2012 - 03/2007
2Interleukin-1 (Interleukin 1)IBA
01/2012 - 06/2006
2LigandsIBA
06/2005 - 01/2003
2ChemokinesIBA
05/2004 - 01/2003
1Dual-Specificity PhosphatasesIBA
11/2021
1VaccinesIBA
01/2021
1Bulk DrugsIBA
01/2021
1Pharmaceutical PreparationsIBA
01/2021
1Immunoglobulin G (IgG)IBA
01/2021
1Immunologic Factors (Immunomodulators)IBA
01/2021
1Immunosuppressive Agents (Immunosuppressants)IBA
01/2021
1NucleotidesIBA
01/2021
1cathelinIBA
01/2021
1Explosive Agents (Explosives)IBA
01/2021
1CathelicidinsIBA
01/2021
1Mitochondrial Proteins (Mitochondrial Protein)IBA
11/2020
1IntegrinsIBA
10/2017
1PerforinIBA
10/2017
1Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
01/2016
1ProlactinIBA
01/2016
1NanovaccinesIBA
01/2015
1HLA Antigens (Human Leukocyte Antigens)IBA
10/2013
1T-Lymphocyte Epitopes (Epitopes, T Lymphocyte)IBA
06/2012
1C-PeptideIBA
06/2012
1HLA-A*02:01 antigenIBA
06/2012
1Type I Tumor Necrosis Factor ReceptorsIBA
08/2011
1Glucose (Dextrose)FDA LinkGeneric
08/2011
1Streptozocin (Streptozotocin)FDA Link
04/2008
1ProinsulinIBA
04/2008
1Adenosine DeaminaseIBA
08/2007
1Adenosine (Adenocard)FDA LinkGeneric
08/2007
1Indoleamine-Pyrrole 2,3,-Dioxygenase (Indoleamine 2,3 Dioxygenase)IBA
06/2007
1Chorionic Gonadotropin (Human Chorionic Gonadotropin)FDA LinkGeneric
06/2007
1Hormones (Hormone)IBA
06/2007
1Substance PIBA
12/2006
1NeuropeptidesIBA
12/2006
1Blood Glucose (Blood Sugar)IBA
06/2006
1Tryptophan (L-Tryptophan)FDA Link
06/2006
1Peptide LibraryIBA
12/2004
1Phosphotransferases (Kinase)IBA
12/2004
1SelectinsIBA
05/2004
1Glycoproteins (Glycoprotein)IBA
02/2003
1Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA
07/2002

Therapy/Procedure

5Therapeutics
01/2019 - 07/2006
3Immunotherapy
01/2016 - 01/2015
1Transplantation
04/2008
1Intra-Arterial Injections
12/2006